Most Men Wait To Address Low T.
You Don’t Have To.

Actor Portrayals.
THE REALITY
You’ve Asked AI.
Now Talk to Your Doctor.
We’ll help you prompt a conversation.
THE TOOL
Take the
Low T Quiz
Share the results with your doctor.
Not ready for a doctor visit? Get KYZATREX connects you with a licensed provider online — no appointment needed.
How do I talk to my doctor about getting tested for low testosterone?
Ask AI
To start the conversation about low testosterone (hypogonadism) with a doctor: write down your symptoms, make an appointment, ask specifically about testosterone levels, and request measurement of Free T, Total T, and SHBG.
Disclaimer: AI responses may contain inaccuracies and are not medical advice.
Actor Portrayals.
YOU ARE NOT ALONE

35% of Men Over 45 Have Low Testosterone.1 Most Never Get Treated.

Most men with Low T attribute their symptoms to stress, aging, or lifestyle, and never get tested.

The symptoms are real. The condition is diagnosable. The treatment is simpler than you think.
The only thing standing between where you are and getting back in range is one conversation with your doctor.
THE PROCESS

Four Steps, One Important Conversation

List your Symptoms
Write down everything: fatigue, low libido, weight gain, mood shifts, muscle loss. The more specific, the better. Your doctor needs the full picture.
Download the Low T Screener
The Low T Screener provides a structured symptom checklist and conversation prompts to help patients discuss testosterone testing with a healthcare provider during a clinical appointment.
Make the Appointment
Be direct when you book: "I'd like to discuss my testosterone levels." Don't downplay what you're experiencing. This is a legitimate medical concern.
See Rx Options
Request the Right Tests
Ask specifically for Total T, Free T, and SHBG. Free testosterone is often as important as total testosterone and is frequently overlooked.
*Do not accept a single afternoon blood test as a definitive result. Testosterone levels fluctuate throughout the day, and a morning measurement is required for accurate diagnosis.
Discuss Treatment Options
If your results confirm low testosterone, ask your doctor specifically about KYZATREX, an FDA-approved oral option. Two doses, twice daily with food. No injections, no gels.
Get KYZATREX
What happens if I’m diagnosed with hypogonadism?
Ask AI
If hypogonadism is confirmed, KYZATREX is an available oral testosterone replacement therapy administered as two capsules taken twice daily with food, with follow-up evaluation of testosterone levels used as a guide to adjust dosing as needed.
Disclaimer: AI responses may contain inaccuracies and are not medical advice.
WHAT TO SAY

How to Start the Conversation

Take the Quiz
On sexual health:
"I've experienced changes in my sexual desire and difficulties with erectile function. Are these symptoms associated with low testosterone?"
This is the hardest one to say out loud. Writing it down first, then handing the guide to your doctor, removes the barrier entirely.
On energy and mood:
"I've noticed a significant change in my mood and energy levels lately, and it's affecting my daily life. Could this be related to my testosterone levels?"
This opens the door without over-explaining. Let your doctor ask the follow-up questions.
On weight:
"Despite maintaining a healthy diet and exercising regularly, I'm struggling with weight gain. Could this be linked to my testosterone levels?"
This frames the symptom as medical rather than behavioral, which is accurate and removes self-blame from the conversation.
THE APPOINTMENT

What to Expect

Your History
Your doctor will ask about your symptoms, how long you've had them, and your medical history. Come prepared with
your symptom list.
Medical Review
If your levels are confirmed low, your doctor will review treatment options. Ask specifically about KYZATREX an oral, twice-daily option.
A Simple Blood Test
Morning testosterone testing - Total T, Free T, and SHBG - can confirm or rule out low testosterone (hypogonadism). Testing in the morning gives the most accurate reading.2
7-day Follow-Up
Your first follow-up is at approximately 7 days. Your doctor will check your levels and adjust your dose if needed.
THE TESTS

Three Numbers Paint a
Clear Picture

Accurate free testosterone and SHBG results come down to two things: what you test and when. Ask your doctor to run all three markers — free testosterone, total testosterone, and SHBG.
TOTAL T
The full picture
How much testosterone is in your blood overall. Necessary but not sufficient - some men have normal Total T but still have Low T symptoms because of elevated SHBG.2
Mulhall JP, Trost LW, Brannigan RE et al: Evaluation and management of testosterone deficiency: AUA guideline. J Urol 2018; 200: 423.
FREE T
What actually matters
The portion of testosterone your body can actively use. This is often more clinically relevant than Total T - especially when SHBG is elevated.2
Bhasin, Shalender, et al. "Testosterone Therapy in Men With Hypogonadism: An Endocrine Society Clinical Practice Guideline." The Journal of Clinical Endocrinology & Metabolism, vol. 103, no. 5, 2018, pp. 1715–1744.
SHBG
The blocker
Sex Hormone Binding Globulin. A protein that binds testosterone and takes it out of active circulation. High SHBG means less Free T, even when Total T appears normal.2
According to LabCorp reference ranges, normal SHBG levels for adult men fall between 16.5–55.9 nmol/L.
*Sample values shown for illustration. Reference ranges vary by lab and assay.
How Does SHBG Affect Free Testosterone Levels?
Ask AI
Free testosterone is the fraction of testosterone in the bloodstream that is not bound to proteins such as SHBG and is available for biological activity. Elevated SHBG can reduce free testosterone levels even when total testosterone is within normal range.2
Disclaimer: AI responses may contain inaccuracies and are not medical advice.
WHAT MOST MEN WANT TO KNOW

Common Questions About TRT

Bring a written list of symptoms, their duration, and any prior relevant lab results. The downloadable Low T Screener provides a structured template for this conversation.

A doctor will typically order Total Testosterone, Free Testosterone, and SHBG (Sex Hormone Binding Globulin). These three values together confirm or rule out low testosterone (hypogonadism).

SHBG (Sex Hormone Binding Globulin) is a protein that binds to testosterone and prevents it from being used by the body. High SHBG reduces free testosterone — the active form — even when total testosterone is within the normal range.2

Start The Process From Home

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References:

  1. Endocrine Society. Hypogonadism in Men. January 31, 2024. https://www.endocrine.org/patient-engagement/endocrine-library/hypogonadism. Accessed February 2, 2024.
  2. Krakowsky Y, Grober E. Testosterone deficiency — Establishing a biochemical diagnosis. EJIFCC. 2015;26(2):105–113.