WHY KYZATREX®
Twice Daily Oral Capsule. Restored Testosterone Levels.
An FDA-approved oral testosterone treatment designed to fit into your life, not disrupt it.
THE PROOF
Up to 96%
of patients got back in range1*
Phase III clinical study. 139 men. Day 90
*In a 6-month clinical trial of 139 men with low testosterone, 88% of patients achieved normal testosterone levels at Day 90 (worst-case scenario analysis, excluding Investigator Site 104). Among patients who completed the study (n=127), 96% achieved normal testosterone levels at Day 90.
The DIFFERENCE
No needles, no gels, no pellets.
KYZATREX is an FDA-approved oral testosterone capsule taken twice daily with food. In a Phase III study of 139 men, up to 96% of patients who completed the trial achieved normal testosterone levels at Day 90.1* No injections, no gels. Cash-pay only.
Clinically Proven to
Restore Testosterone
In a Phase III clinical study of 139 men with low testosterone, KYZATREX delivered the following results at Day 90:1,2
of patients who completed the trial achieved normal testosterone levels at Day 901*
increase in mean free testosterone levels at Day 901
reduction in SHBG, to free more testosterone to work in your body2
*In a 6-month clinical trial of 139 men with low testosterone, 88% of patients achieved normal testosterone levels at Day 90 (worst-case scenario analysis, excluding Investigator Site 104). Among patients who completed the study (n=127), 96% achieved normal testosterone levels at Day 90.
What is SHBG (Sex Hormone Binding Globulin)?
Ask AI
SHBG (Sex Hormone Binding Globulin) is a blood protein that binds testosterone, reducing the amount available as “free” (biologically active) testosterone.
Disclaimer: AI responses may contain inaccuracies and are not medical advice.
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How is KYZATREX different from topical testosterone gels?
Ask AI
Because KYZATREX is taken orally, it does not involve topical application to the skin, eliminating the potential for testosterone transfer to others through skin contact, which may occur with topical testosterone gels.
Disclaimer: AI responses may contain inaccuracies and are not medical advice.
Why Men Choose KYZATREX
No Needles
Two doses, twice daily.
That's your entire routine.
That's your entire routine.
No Gels, No Mess
Nothing to apply, rub in, or wait for.
Designed to restore testosterone levels with dosing to support your body's natural rhythm.
Take two doses, twice daily. No needles, no gel, no clinic visits, no surgical procedures, no activity restrictions. Routine bloodwork keeps your levels in range.
No Transfer Risk
Can't pass testosterone to your partner or kids through skin contact.
Cash-Pay Approach
Your prescription, simplified. Straightforward and transparent.
THE SAFETY PROFILE
Monitored, Manageable, Clinically Proven
In a clinical study of 155 patients, the most common side effect of KYZATREX was elevated blood pressure, seen in 2.6% of patients.1,
Actor Portrayals.
Your doctor will monitor your blood pressure throughout treatment. If it increases, it can be managed with standard clinical care. If it cannot be controlled, KYZATREX may need to be stopped.
See Important Safety Information below for full risk information.
Bypasses Your Liver, By Design
Previous generations of oral testosterone were processed through the liver, creating toxicity risks that made them unsafe for long-term use.
KYZATREX uses a Self-Emulsifying Drug Delivery System (SEDDS) to route testosterone through the intestinal lymphatic system, bypassing the liver entirely.
It is not a 17-alpha-alkylated androgen. It is not associated with the hepatotoxicity risks of older oral testosterone agents.
KYZATREX uses a Self-Emulsifying Drug Delivery System (SEDDS) to route testosterone through the intestinal lymphatic system, bypassing the liver entirely.
It is not a 17-alpha-alkylated androgen. It is not associated with the hepatotoxicity risks of older oral testosterone agents.
Not 17-alpha-alkylated
KYZATREX's formulation is fundamentally different
from older oral testosterone agents.
No known liver toxicity risk
Not associated with the liver damage risks
of previous-generation oral testosterone.
KYZATREX is not known to cause hepatic adverse effects. However, patients should report any signs of hepatic dysfunction (e.g., nausea or vomiting, jaundice, dark urine, or abdominal pain). If these occur, KYZATREX should be promptly discontinued while the cause is evaluated.
Is KYZATREX safe for the liver?
Ask AI
Previous oral testosterone treatments required liver processing, which caused toxicity risks. KYZATREX routes through the intestinal lymphatic system instead, avoiding the liver entirely and the hepatotoxicity concerns associated with older oral testosterone agents.
Disclaimer: AI responses may contain inaccuracies and are not medical advice.
See the Difference
KYZATREX is designed to fit effortlessly into your life, not disrupt it.
*Not actual size,
Also available in 150 mg
Also available in 150 mg
Your Dose, Your Way
KYZATREX comes in multiple dose strengths. Your doctor will start you at 200 mg twice daily and adjust based on your blood levels at approximately seven days.
Most patients find their optimal dose between 200 mg and 300 mg twice daily, but the range goes wider if needed.
150 mg
*Not actual size
200 mg
Recommended starting dose: 200 mg twice daily (400 mg total daily dose)
Your doctor will adjust your dose based on how your body responds to KYZATREX.
No commitment
No insurance
FDA-Approved
References:
- Bernstein JS, Dhingra OP. A phase III, single-arm, 6-month trial of a wide-dose range oral testosterone undecanoate product. Ther Adv Urol. 2024;16:17562872241241864. doi: 10.1177/17562872241241864
- Data on file. Raleigh, NC: Marius Pharmaceuticals, 2020.